Treatment for spasmodic dysphonia: limitations of current approaches

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Botulinum toxin injections for the treatment of spasmodic dysphonia.

BACKGROUND The use of botulinum toxin for the treatment of spasmodic dysphonia is currently the treatment of choice for management of this neurological voice disorder. Over the past 20 years, botulinum toxin has been used to treat both adductor and abductor forms of the disorder, with vocal improvement noted after treatment for both. A large number of studies have attempted to document the effi...

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Thyroarytenoid Muscle Ablation for Treatment of Spasmodic Dysphonia

Adductor spasmodic dysphonia is the most common form of laryngeal dystonia and comprises about 80% of all laryngeal dystonias. It is characterized by strained and strangled voice quality causing significant impairment to the patient. This article focuses on the surgical treatment of adductor spasmodic dysphonia by thyroarytenoid muscle ablation. It provides longlasting control of symptoms and p...

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Outcomes of botulinum toxin treatment for patients with spasmodic dysphonia.

BACKGROUND Spasmodic dysphonia (SD) is a focal dystonia of the larynx. Although individuals with SD have variable degrees of difficulty in everyday communication and speaking, many report significant impairments. The impact of SD on the quality of life of people with the disorder has not been well measured. OBJECTIVES To assess the impact of SD using a voice-specific, validated outcomes instr...

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Brainstem pathology in spasmodic dysphonia.

Spasmodic dysphonia (SD) is a primary focal dystonia of unknown pathophysiology, characterized by involuntary spasms in the laryngeal muscles during speech production. We examined two rare cases of postmortem brainstem tissue from SD patients compared to four controls. In the SD patients, small clusters of inflammation were found in the reticular formation surrounding solitary tract, spinal tri...

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Historical approaches to the treatment of Adductor-Type Spasmodic Dysphonia (ADSD): review and tutorial.

Adductor-type spasmodic dysphonia (ADSD) is a voice disorder of uncertain, though likely neurogenic origin. Symptoms of the disorder include mild to profound "strain and strangle" sensations during voiced speech tasks that, in the most severe form, are physically and psychologically debilitating. Over the years, treatment approaches have evolved from behavioral attempts at voice modification, t...

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ژورنال

عنوان ژورنال: Current Opinion in Otolaryngology & Head and Neck Surgery

سال: 2009

ISSN: 1068-9508

DOI: 10.1097/moo.0b013e32832aef6f